王怀生,男,1962年12月出生,南京大学分析化学专业博士,教授,苏州大学兼职博士生导师,聊城大学硕士生导师、材料科学与工程学院党总支书记,山东省化学化工学会理事,中国仪器仪表学会分析仪器分会电化学分析专业委员会委员。
科研方向为电分析化学,科研工作主要在电化学生物传感器、化学修饰电极以及纳米材料在电分析化学中的应用等方面开展工作,在聚噻吩导电聚合物及其复合材料修饰电极、新型酶传感器、DNA的直接电化学检测和DNA损伤检测等方面取得了一定成果。科研成果多次获山东省教育厅优秀科研成果二三等奖和聊城大学优秀科研成果一二等奖。
参加国家自然科学基金重大和面上项目多项,主持完成和在研国家自然科学基金项目二项(DNA损伤的直接电化学检测及其损伤机制研究,No.20475024,聚噻吩类导电聚合物/无机纳米材料杂化膜修饰电极的制备与应用研究,No. 20775031),主研山东省自然科学基金一项。
近几年代表成果:
1.A novel hydrogen peroxide sensor based on the direct electron transfer of horseradish peroxidase immobilized on silica-hydroxyapatite hybrid film.
Huai-Sheng Wang* et al, Biosens. Bioelectron. In press.
2. Electrochemical study on DNA damage based on the direct oxidation of 8- hydroxydeoxyguanosine at an electrochemically modified glassy carbon electrode. Huai-Sheng Wang,* et al. Electroanalysis, 2008, 20(15), 1684-1689.
3. Electrochemical Performance of 8-Oxodeoxyguanosine and its Detection at Poly(3-methylthiophene) Modified Glassy Carbon Electrode
Huai-Sheng Wang* et al, Biosens. Bioelectron. 2007, 22, 1245–1250.
4.Highly selective and sensitive determination of dopamine using a Nafion/carbon nanotubes coated Poly(3-methylthiophene) modified electrode
Huai-Sheng Wang* et al., Biosens. Bioelectron., 2006, 22, 664-669.
5.Electrochemical Study of the Interactions of DNA with Redox-Active Molecules Based on the Immobilization of dsDNA on the Sol-Gel Derived Nano Porous Hydroxyapatite-Polyvinyl Alcohol Hybrid Material Coating
Huai-Sheng Wang,* et al. Electroanalysis 17, 2005, 1854–1860.
6. Study on the electrochemical behavior of epinephrine at a poly(3-methylthiophene) modified glassy carbon electrode
Huai-Sheng Wang et al., J. Electroanal. Chem,. 2004, 570, 83-90.
7. Simultaneous determination of guanine and adenine in DNA using an electochemically pretreated glassy carbon electrode.
Huai-Sheng Wang et al. Anal. Chim. Acta, 2002, 461, 243-247.
8. Adsorptive stripping voltammetric detection of single-stranded DNA at electrochemically modified glassy carbon electrode.
Huai-Sheng Wang et al. Electroanalysis, 2002, 14, 1615-1620.
9.新型DNA电化学传感器的研制及其用于DNA氧化性损伤检测的研究
王怀生*等,高等学校化学学报,2005, 26(10), 1812-1816.
10.DNA-纳米多孔羟基磷灰石修饰电极用于研究DNA与亚甲基蓝的相互作用
王怀生*等,化学学报,2006, 64(22), 2259-2264.